IN VITRO ANTHELMINTIC EFFICACY OF METHANOL STEM-BARK EXTRACT OF  ANOGEISSUS LEIOCARPUS AGAINST ASCARIDIA GALLI INFECTION IN POULTRY

S. F. Yahaya; M. C. Uchaegbu; A. M. Tauheed; P. I. Kobo; H. Aliu; P. O. Yusuf; M. Shittu; M. M. Suleiman

doi:10.51791/njap.vi.4374

Authors

S. F. Yahaya Ahmadu Bello University, Zaria
M. C. Uchaegbu Ahmadu Bello University, Zaria
A. M. Tauheed Ahmadu Bello University, Zaria
P. I. Kobo Ahmadu Bello University, Zaria
H. Aliu Ahmadu Bello University, Zaria
P. O. Yusuf Ahmadu Bello University, Zaria
M. Shittu Ahmadu Bello University, Zaria
M. M. Suleiman Ahmadu Bello University, Zaria

DOI:

https://doi.org/10.51791/njap.vi.4374

Keywords:

Anthelmintic, stem-bark, Anogeissus leiocarpus, in vitro, Ascaridia galli

Abstract

Ascaridia galli is an important gastrointestinal nematode of birds that has been implicated as one of the most common parasites of poultry. The main method of controlling nematode parasites of poultry has been through the use of synthetic anthelmintics. However, these drugs are scarcely available to poor farmers or rural communities. Anogeissus leiocarpus stem-bark methanol extract (AME) was investigated for its in vitro anthelmintic activity against Ascaridia galli. The extract was prepared by cold maceration and five different concentrations of the extract was studied (4 mg/ml, 2 mg/ml, 1 mg/ml, 0.5 mg/ml and 0.25 mg/ml). Albendazole and 0.1M sulphuric acid were used as positive and negative control respectively. The IC50 for the egg hatch assay was 0.25 mg/ml. There was no significant difference in the egg hatch inhibitory (EHI) activity of the extract when compared to albendazole. Higher concentrations of the extract had superior larvicidal activity. Anogeissus leiocarpus (A. leiocarpus) could find application in anthelmintic therapy in veterinary practice